Organic Chemistry, Coumarin, Antioxidant, Radical scavenging activity, DPPH, Imidazobenzothiazole, Spectrophotometric study, natural products, heterocyclic chemistry, organic synthesis
Two coumarin derivatives, namely 3-benzo[d]imidazo[2,1-b]thiazol-2-yl)-chromen-2-one (IBT) and 3-(8-hydroxy-imidazo[1,2-a]pyridin-2-yl)-chromen-2-one (IMPY), were synthesized and their antioxidant properties were investigated using spectrophotometric methods. The percentage of radical scavenging activity (%RSA) for each compound was determined using the α, α-diphenyl-β-picrylhydrazyl (DPPH) assay method. A comparative analysis of the %RSA values obtained with those of ascorbic acid, a well-known antioxidant, revealed that both IBT and IMPY exhibited considerable antioxidant activity, indicating their potential as antioxidants. IBT demonstrated moderate antioxidant properties, with an %RSA value of 70.65% at a concentration of 10-3 M, which was slightly lower than that of ascorbic acid, but still significant.
URN:NBN:sciencein.jmc.2023.582
Two coumarin derivatives, namely 3-benzo[d]imidazo[2,1-b]thiazol-2-yl)-chromen-2-one (IBT) and 3-(8-hydroxy-imidazo[1,2-a]pyridin-2-yl)-chromen-2-one (IMPY), were synthesized and their antioxidant properties were investigated using spectrophotometric methods. The percentage of radical scavenging activity (%RSA) for each compound was determined using the α, α-diphenyl-β-picrylhydrazyl (DPPH) assay method. A comparative analysis of the %RSA values obtained with those of ascorbic acid, a well-known antioxidant, revealed that both IBT and IMPY exhibited considerable antioxidant activity, indicating their potential as antioxidants. IBT demonstrated moderate antioxidant properties, with an %RSA value of 70.65% at a concentration of 10-3 M, which was slightly lower than that of ascorbic acid, but still significant. URN:NBN:sciencein.jmc.2023.582
Journal of Molecular Chemistry
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