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MnO2 nanostructures: A review of synthesis methods and multifunctional applications
Materials NanoScience Read More Keywords: item categories Manganese dioxide (MnO₂) nanorods have emerged as a promising class of one-dimensional nanomaterials due to their excellent electrochemical properties, high surface area, and structural tunability. These characteristics make MnO₂ nanorods highly suitable for applications in energy storage, catalysis, environmental remediation, and the biomedical field. The synthesis of MnO₂…
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Effect of sonication on structural and functional characteristics of protein concentrate obtained from manipur black rice (Oryza sativa L.)
Journal of Integrated Science and Technology Read More Keywords: item categories The black rice manipur protein concentrate (BRPC) was ultrasonicated at intervals of 5, 15, 25, and 35 min. Ultrasonication treatment profoundly altered the structure and functionality of BRPC while enhancing the solubility and emulsifying activity index of the material. Particle size, surface hydrophobicity, the…
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Evaluating surgical margins in Pelvic tumour resections: Implications for oncological success in integrative medicine
Integrated Research Advances Read More Keywords: item categories Introduction: Achieving safe surgical margins in pelvic bone and soft tissue tumor resections remains a significant challenge.1-3 Despite advancements in diagnostic and therapeutic modalities, the prognosis for pelvic tumors continues to be poorer than that of tumors affecting the long bones.4-6 Clear surgical margins are essential in…
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The role of microbiota in autoimmune disease pathogenesis: Mechanisms and therapeutic implications
Journal of Integrated Science and Technology Read More Keywords: item categories The role of the human microbiome in autoimmune pathogenesis. This review is intended to explore the cause-effect phenomenon in the interaction between microorganism and autoimmune disease through reference to data during 2000 till 2025. We discuss the influence of early-life colonization of the microbiota…
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Paritaprevir (S5404) evaluation as an effective therapeutic candidate against Japanese Encephalitis virus
Journal of Integrated Science and Technology Read More Keywords: item categories Drug repurposing offers an inexpensive and time- saving approach to fast-track therapeutic development by leveraging the established safety and efficacy profiles of FDA-approved drugs. This study evaluates the potential of S5404_Paritaprevir as a repurposed antiviral agent targeting the RNA-dependent RNA polymerase (RdRp) and NS2B/NS3…
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Uncovering the inflammatory axis: Clinical relevance of Irisin and Myeloperoxidase in adolescent bronchial asthma
Chemical Biology Letters Read More Keywords: item categories Bronchial asthma is a chronic inflammatory disease with airway blockage, hyper-responsiveness. Key biomarkers like irisin, myeloperoxidase (MPO), and glucose regulate inflammation and metabolic dysfunction. Irisin is a novel parameter for adolescents asthma. In this study assessed prognostic significance of irisin and MPO in predicting asthma outcomes. A…
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Micellar nanostructures from G1-Oligoglycerol-based amphiphiles with bioactive hydrophobic segments for enhanced therapeutic release
Journal of Integrated Science and Technology Read More Keywords: item categories In this study, we present the rational design and synthesis of two novel bioactive dendritic amphiphiles, constructed from a G1-oligoglycerol scaffold conjugated with α-tocopherol (vitamin E) and 3,4,5-trimethoxy-cinnamic acid as hydrophobic moieties. Utilizing modular coupling strategies, the amphiphiles were successfully synthesized and demonstrated spontaneous…
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Structurally robust and biodegradable amide-linked dendritic amphiphiles for pH-responsive nanocarriers for enhanced hydrophobic drug delivery
Chemical Biology Letters Read More Keywords: item categories The development of biocompatible and structurally robust amphiphilic nanocarriers is crucial for enhancing the solubility, stability, and targeted delivery of poorly water-soluble therapeutics. In this study, we report the design, synthesis, and physicochemical evaluation of four new non-ionic dendritic amphiphiles derived from glycerol-based dendrons incorporating biodegradable amide…
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Uncovering the inflammatory axis: Clinical relevance of Irisin and Myeloperoxidase in adolescent bronchial asthma
Chemical Biology Letters Read More Keywords: item categories Bronchial asthma is a chronic inflammatory disease with airway blockage, hyper-responsiveness. Key biomarkers like irisin, myeloperoxidase (MPO), and glucose regulate inflammation and metabolic dysfunction. Irisin is a novel parameter for adolescents asthma. In this study assessed prognostic significance of irisin and MPO in predicting asthma outcomes. A…
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Alkaline Earth-metal ions transfer in cell membrane through [SiO–GeO] or [SiO–SnO] nanoclusters: A biomaterials modeling investigation
Materials NanoScience Read More Keywords: item categories Ge,Sn/Si-based nanoparticles are used as excipients in pharmaceutical technology. Recently, silicon/germanium oxide has emerged as drug delivery systems. Therefore, in this article, it has been evaluated the promising alternative alkaline earth metals of beryllium-ion, magnesium-ion, calcium-ion delivery. This paper reports the presence of human cells of an additional…
