Synthesis of novel bithiazole–pyrazole hybrid compounds linked via carbohydrazide and their antimicrobial SAR evaluation​

Journal of Molecular Chemistry Read More Keywords: item categories  A novel series of N′-((5-substituted-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene)-5-isobutyl-[2,2′-bithiazole]-4-carbohydrazide derivatives (11a to 11j) was synthesized via a stepwise condensation strategy. The structures were confirmed using 1H NMR, 13C NMR, FTIR, LC-MS, and elemental analysis, with HPLC confirming ≥95% purity. All compounds were evaluated for antimicrobial activity against Gram-positive (S. aureus,

Synthesis of novel bithiazole–pyrazole hybrid compounds linked via carbohydrazide and their antimicrobial SAR evaluation​ Read More »

iScience
Scroll to Top