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Identification of potential phytochemicals of A. archangelica against SARS COV-2 main protease receptor (Retracted)
Articles, Covid-19, SARS-COV-2, Molecular docking, Phytochemicals Retraction Note: This article has been marked for retraction. Issue: Conflict of interest / author contributions. Abstract: The proteins N and M, 3′-5′ exoribonuclease (nsp14), viral proteases, and RNA dependent RNA polymerase (RdRp) are required for different stages of SARS-CoV-2 viral replication. For many antiviral therapies, these are thus…
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Click Chemistry reactions: Fundamental mechanisms review of molecular conjugationsJournal of Molecular Chemistry
Organic Chemistry, Click Chemistry, Triazoles, Bioorthogonal Chemistry, Reaction Mechanisms, Catalysis The click chemistry reactions are the one leading conjugation protocols where two molecules can form the bonds in simple reaction conditions and at faster reaction rate. Understanding of the different methods and catalysts used for the click chemistry reactions provides the platforms for exploration of…
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Synthetic small molecule based anti-viral chemical drugs as treatment options for COVID-19: New updates reviewJournal of Molecular Chemistry
Medicinal Chemistry, small molecule drugs, Heterocyclic drugs, Covid-19, SARS-COV-2, Corona Virus, Viral infections, Viral therapeutics The SARS-CoV-2 outbreak and subsequent pandemic that began in late 2019 has presented a significant challenge to global health. Currently, numerous small-molecule therapeutic candidates have been developed that can inhibit both the infection and replication of SARS-CoV-2, and may even…
