Medicinal Chemistry, Oxidative stress, ulcers, aging, cardiovascular diseases, pulmonary disease, hepatic failure, diabetes, cancer, molecular mechanism, oxidation pathways Oxidative stress arises from an imbalance between reactive oxidants and the antioxidant defense system in cells. This article outlines the mechanisms and effects of oxidative stress on disease onset. Reactive oxidants, like superoxide anion and hydrogen peroxide, […]

Review Articles, Catalyst, Heteroatom bonds, organic transformations, Organic synthesis, Heck reaction, heterocyclic chemistry, C-H activation Transition metal catalysts have played an important role in forming carbon–carbon and carbon–heteroatom bonds. Formation of these bonds by using various transition metals such as Pd, Ni, Ru, Rh has been extensively investigated and documented in the literature. Recent years

Review Articles, Mass spectrometry, Analyzers, FT-ICR MS, Ionization Methods, Analytical Methods The application of mass spectrometry (MS) for structural elucidation in life sciences and bioanalytical approaches has become progressively significant. The recent advancements in MS have led to remarkable improvements in mass resolving power, mass accuracy, isotopic abundance accuracy, and accurate mass multiple-stage MS (n)

Medicinal Chemistry, Quinoline, Binding affinity, Biological activity, Antibiotic, Molecular docking, Molecular modeling, In-silico study, simulations The quinolines based drugs and its analogues are widely used as a medicinal drug. In this study, five compounds from quinoline-based pharmaceuticals have been discovered using virtual screening with Autodock software, with binding affinities ranging from 6.6 to 5.4 kcal/mol.

Nanochemistry & Materials Chemistry, Nanofilm, Polymer, Corrosion, Material protection, Chemistry of materials One of the most notable adverse effects of acidifying air quality is damage to materials exposed to the atmosphere. Systematic fields and laboratory experiments have been done to understand the mechanisms underlying the impacts of pollutants on the measurement of damage and estimate

Review Articles, Polyethers, Novozyme-435, click chemistry, dendronized polymers, nanocarriers Click chemistry and bio-orthogonal chemistry stands out as dynamic tools for chemists and biologists to snap together chemical entities as well as chemical and biological building blocks with just a click to construct a variety of intricate molecular structures with ease, rapidity, and selectivity. The ground-breaking

Organic Chemistry, Coumarin, Antioxidant, Radical scavenging activity, DPPH, Imidazobenzothiazole, Spectrophotometric study, natural products, heterocyclic chemistry, organic synthesis Two coumarin derivatives, namely 3-benzo[d]imidazo[2,1-b]thiazol-2-yl)-chromen-2-one (IBT) and 3-(8-hydroxy-imidazo[1,2-a]pyridin-2-yl)-chromen-2-one (IMPY), were synthesized and their antioxidant properties were investigated using spectrophotometric methods. The percentage of radical scavenging activity (%RSA) for each compound was determined using the α, α-diphenyl-β-picrylhydrazyl (DPPH) assay

Journal of Molecular Chemistry Read More Keywords: item categories  Polyphenols, the most prevalent and naturally occurring substances have synergistic qualities that may have positive effects on human’s health. When synergistic foods are combined, the evidence for health benefits is greater than when the foods are consumed separately. Nutrient deficiency is a well-known phenomenon in many

Articles, Covid-19, SARS-COV-2, Molecular docking, Phytochemicals Retraction Note: This article has been marked for retraction. Issue: Conflict of interest / author contributions. Abstract: The proteins N and M, 3′-5′ exoribonuclease (nsp14), viral proteases, and RNA dependent RNA polymerase (RdRp) are required for different stages of SARS-CoV-2 viral replication. For many antiviral therapies, these are thus